Mestag Therapeutics

25 Nov, 2024
Briony Quested
Mestag Therapeutics is an immunotherapy company that develops innovative treatments for cancer and inflammatory disease patients through insights into fibroblast-immune cell interactions.
Thumbnail
Mestag CEO Susan Hill. Courtesy – Mestag Therapeutics.

The company’s expertise in fibroblast biology facilitates its pipeline of first-in-class bespoke antibody programs. Mestag is accelerating the development of immunotherapies to treat the 50-70 per cent of cancer patients who fail to respond to drugs that block checkpoint protein inhibitors.

The company, led by CEO Susan Hill, is also developing immunotherapies for inflammatory disease patients to increase the rate of durable clinical remission. Mestag recently appointed a group of top cancer biology and immunology advisors to help guide its first-in-class oncology program, M300 — a tertiary lymphoid structure (TLS) induction to treat solid tumours.

In October 2024, Mestag entered into a license and collaboration agreement with MSD to identify novel targets for the development of therapies against inflammatory diseases.

Career opportunities at Mestag Therapeutics