Horizon Discovery followed its Business Weekly Awards success by winning a Queen’s Award for Enterprise. Horizon provides research tools to support translational genomics research and the development of personalised medicines.

Listed on the London Stock Exchange since 1984, Cambridgeshire ink jet printing company, Domino UK, reported sales for the year to October 31, 2010 of £300 million – a record growth of 17 per cent over the previous year and the group’s 32nd year of consecutive growth.

An online supplier of antibody products for Life Sciences research organisations around the world, Abcam is enabling scientists to identify more effective solutions to healthcare problems.

Peterborough based British Sugar is the leading supplier of sugar to the UK market. Its products are represented in the leading brands of all the major global food and drink manufacturers.

The Cambridge based enterprise search software specialist continues to dominate the global market in this niche space. Founded in 1996 and utilising a unique combination of technologies borne out of research at Cambridge University, Autonomy has experienced a meteoric rise.

AVEVA’s rise and rise is one of the largely unsung success stories from the Cambridge Phenomenon years. Today the company is the world's leading engineering IT software provider to the plant, power and marine industries.

A developer of human monoclonal antibody therapeutics, CAT was the first UK biotech to jointly develop a 'blockbuster' drug. The company was acquired by AstraZeneca in 2006 for £702m and subsequently incorporated into MedImmune, which continues to grow in Cambridge.

CSR became the first company to win the Business of the Year title two years running. Fast forward to current day and CSR packed more muscle onto its share price after posting Q4 revenue and margin at the upper end of market guidance to the end of December.

Cambridge Silicon Radio spun out of Cambridge Consultants in 1998 – in fact it was thrown out as management told the co-founders that it had world-beating wireless technology and should stay in the nest no longer.

What a game-changing company Acambis was – and one that came to the forefront at a time of incredible global political flux due to the emerging threat of bioterrorism.

When Business Weekly named the low fares airline as Business of the Year, many felt that as an Irish based carrier, it should be excluded.

Another great spot by Business Weekly. Virata provided communications software and semiconductors to manufacturers of DSL, wireless, satellite, and other broadband networking equipment.

The victory for Advanced RISC Machines, the Acorn spin-out, was historic. ARM now ships more chips than Intel but Business Weekly spotted ARM’s potential years ahead of the pack.

Waymade Healthcare in Essex is a pharmaceutical company with a turnover placing it within the top 10 UK pharma league. It supplies and distributes branded and generic pharmaceutical products.

The company, based at Melbourn Science Park, remains the only tech consultancy to have won the Business of the Year Award. It was a remarkable achievement as few recognised the powers behind the thrones of leading tech and industrial players.

Based in Northampton at the time of the award, Electrocomponents remains the world’s largest distributor of electronics and maintenance products serving 1.5 million customers worldwide.